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Special Report Small-Cap Standouts: These 3 Stocks Rose Over 300% in 2025By Leo Miller. First Published: 1/3/2026. 
Quick Look - While small caps as a whole generated lower returns than large caps in 2025, three interesting names bucked this narrative.
- A cancer screening company and two satellite operators saw their shares rise 300% or more.
- See where analysts are forecasting upside and understand vital considerations pertaining to smaller stocks.
In 2025, small-cap stocks underperformed. The Russell 2000 Index, which tracks the performance of 2,000 U.S. small-cap stocks, delivered a total return of about 13% in 2025. That lagged the S&P 500 Index's roughly 18% total return, which tracks U.S. large-cap stocks. Despite the broader small-cap weakness, three names stood out for exceptional performance in 2025. Below, we highlight three stocks that returned 300% or more. Each started 2025 in small-cap territory but, after their gains, have moved into mid-cap status. GRAL Catapults on Early Cancer Detection Enthusiasm Amazon's Layoffs Were Just the Beginning
Amazon just slashed 30,000 jobs – the largest layoff in its history – and almost no one's talking about the real reason why. A former hedge fund manager says it's part of a much bigger shift. One that could reshape how we all work, invest, and build wealth in the years ahead. He's spent the last decade preparing for this moment... and just released something that could help everyday Americans get ahead, while there's still time. Full story here Healthcare stock GRAIL (NASDAQ: GRAL) rose roughly 380% in 2025. Its market capitalization moved from well below $1 billion to about $3.3 billion. GRAIL's main product is the Galleri multi-cancer early detection test. Early detection significantly improves cancer survival rates, which has driven investor interest in the product. Notably, only about five cancers have standardized screening methods, yet roughly 70% of cancer deaths stem from other types. GRAIL designed Galleri to detect more than 50 different cancers. In a recent study, the company reported Galleri increased early cancer detection by more than sevenfold when added to traditional screening methods. Today, Galleri primarily generates revenue from out-of-pocket payments. GRAIL expects to file for Premarket Approval (PMA) with the U.S. Food and Drug Administration in the first quarter of 2026. If approved, commercial insurers would be far more likely to cover the test, opening a substantial new sales channel. That potential approval is a major driver of investor enthusiasm. The MarketBeat consensus price target of $97.50 reflects analyst optimism and implies roughly 14% upside from current levels. PL Blasts Off, Combining AI with Geospatial Imagery Planet Labs PBC (NYSE: PL) enjoyed a huge 2025, with shares rising about 390%. Planet operates hundreds of satellites to capture medium- to high-resolution images of Earth and pairs that imagery with artificial intelligence to help customers make decisions. The company generates revenue through subscriptions to its cloud platform and satellite services. Demand has accelerated, particularly from government customers. Its Dec. 10 earnings report sent shares up 35% in a single day, driven by defense and intelligence revenue rising over 70%. The firm reported a backlog of roughly $735 million — about 2.6 times its trailing 12 months (TTM) revenue of $282 million — which supports significant growth potential. Planet Labs also produced positive free cash flow for the second consecutive quarter. The MarketBeat consensus price target of $14.74 currently implies about 25% downside. However, the average of targets updated after the company's latest earnings report is $18.19, implying roughly 7.7% downside. Planet Labs remains one to watch; a meaningful pullback could create a more attractive entry point. Updated Targets Eye Strong Upside in VSAT After Huge 2025 Run Last up is Viasat (NASDAQ: VSAT), which gained approximately 305% in 2025 and now has a market cap near $4.7 billion. Viasat is another satellite-focused company, concentrating on internet and data connectivity. While it shares similarities with AST SpaceMobile (NASDAQ: ASTS), Viasat primarily serves aviation, maritime and government customers rather than consumer-focused telecom operators. For example, Viasat provides in-flight wireless connectivity to thousands of commercial and business aircraft. The U.S. government was its largest customer in fiscal 2025, accounting for 18% of revenue. (Viasat is currently in fiscal 2026.) Revenue grew by only 2% year-over-year last quarter, but awards rose 17% to nearly $1.5 billion and backlog climbed to almost $3.9 billion. The MarketBeat consensus price target of $32.75 implies about 5% downside. However, analyst targets updated after the company's Nov. 7 earnings report average $49, suggesting roughly 37% upside potential. GRAL, PL, VSAT: Deep Research Is Paramount Overall, GRAL, PL and VSAT delivered incredible returns in 2025. While these stocks are exciting, investors should remember that smaller companies — especially those that have run up this dramatically — can be highly volatile. Confidence in each company's long-term outlook is essential. Investors should conduct thorough due diligence before making investment decisions.
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