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Sunday's Bonus Story Small-Cap Standouts: These 3 Stocks Rose Over 300% in 2025By Leo Miller. Posted: 1/3/2026. 
Key Points - While small caps as a whole generated lower returns than large caps in 2025, three interesting names bucked this narrative.
- A cancer screening company and two satellite operators saw their shares rise 300% or more.
- See where analysts are forecasting upside and understand vital considerations pertaining to smaller stocks.
In 2025, small-cap stocks generally underperformed. The Russell 2000 Index, which tracks the performance of 2,000 U.S. small-cap stocks, delivered a total return of roughly 13% for the year. That lagged the S&P 500 Index—our proxy for large-cap U.S. stocks—which returned about 18%. Despite the broader underperformance, three small-cap companies stood out for exceptional gains. Below, we profile three stocks that rose 300% or more in 2025. Each began the year in small-cap territory but, after their rallies, has moved into mid-cap range. GRAL Catapults on Early Cancer Detection Enthusiasm Healthcare stock GRAIL (NASDAQ: GRAL) climbed roughly 380% in 2025. Its market capitalization moved from well below $1 billion to about $3.3 billion. GRAIL's primary product is the Galleri Multi-Cancer Early Detection test. Early detection dramatically improves cancer survival rates, which has driven investor interest in Galleri. Only a handful of cancers have established population-level screening programs, yet roughly 70% of cancer deaths come from cancers outside that group. Galleri is designed to detect more than 50 types of cancer; a recent study reported Galleri increased early cancer detection by more than sevenfold when added to traditional screening. Currently, Galleri's revenue comes mostly from out-of-pocket payments, but GRAIL expects to seek Premarket Approval (PMA) from the U.S. Food and Drug Administration (FDA) in the first quarter of 2026. FDA approval would significantly improve the likelihood that commercial insurers cover the test, potentially opening a much larger sales channel. That approval potential is a key driver of investor enthusiasm. The MarketBeat consensus price target of $97.50 reflects analyst optimism and implies roughly 14% upside from current levels. PL Blasts Off, Combining AI with Geospatial Imagery Planet Labs PBC (NYSE: PL) delivered a standout 2025, with shares rising just under 390%. Planet operates hundreds of satellites that capture medium- to high-resolution images of Earth and pairs that imagery with artificial intelligence to help customers make better decisions. The company primarily sells subscriptions to its cloud-based platform and satellite-related services. Demand has materialized, particularly among government customers. Its Dec. 10 earnings report sparked a 35% one-day jump in the stock, driven by defense and intelligence revenue that rose more than 70%. Planet reported a backlog around $735 million—roughly 2.6 times its trailing 12-month revenue of $282 million—providing runway for growth. The company also posted positive free cash flow for the second consecutive quarter. The MarketBeat consensus price target of $14.74 implies about 25% downside from current prices. However, analyst targets updated after the latest earnings report average $18.19, which would imply roughly 7.7% downside. Given the recent momentum, a meaningful pullback could present a more attractive entry point for investors who want exposure to geospatial AI. Updated Targets Eye Strong Upside in VSAT After Huge 2025 Run Finally, Viasat (NASDAQ: VSAT) rallied about 305% in 2025, lifting its market cap to near $4.7 billion. Like Planet Labs, Viasat operates satellites, but it focuses on internet and data connectivity for aviation, maritime, and government customers rather than primarily addressing consumer telecom operators such as AST SpaceMobile (NASDAQ: ASTS). Viasat supplies in-flight connectivity to thousands of commercial and business aircraft. The U.S. government was its largest customer in fiscal 2025, accounting for about 18% of revenue. Note that Viasat is currently in fiscal 2026. Revenue grew just 2% in the most recent quarter, but awards rose 17% to nearly $1.5 billion and backlog climbed to almost $3.9 billion. The MarketBeat consensus price target of $32.75 implies about 5% downside. However, analyst targets updated after the company's Nov. 7 earnings average $49, suggesting roughly 37% upside potential. GRAL, PL, VSAT: Deep Research Is Paramount GRAL, PL, and VSAT delivered exceptional returns in 2025, but investors should remember that smaller stocks—especially those that have just produced triple-digit gains—carry elevated risk and can be highly volatile. Confidence in a company's long-term fundamentals is essential before committing capital. Investors should perform thorough due diligence and consider how these names fit within a diversified portfolio before making investment decisions.
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