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Take A Look At (VNRX) While It's Still Early…
January 8, 2026
Almost Time | See Why (VNRX) is at the Very Top of My Radar Ahead of the Bell
Dear Reader,
What if the next major shift in diagnostics doesn't start with a scalpel… but with a standard blood draw? That's the lane VolitionRx Limited (VNRX) is charging down — using epigenetic signals inside circulating DNA to help flag cancer and sepsis earlier, faster, and at a cost profile designed for real-world scale. No invasive procedures. No complex workflow overhaul. Just smarter information pulled from what's already in the bloodstream. After more than a decade building its platform and refining the science, (VNRX) now looks like it's moving from research-mode into execution-mode. And the latest milestones — from clinical progress to expanding IP and partner discussions — suggest the commercial rollout is starting to take shape. That's why (VNRX) just hit our radar… and why it's topping our watchlist this morning — Thursday, January 8, 2026. And (VNRX)'s progress is not going unnoticed. Several analysts covering the company continue to point to what they see as a meaningful gap between its current valuation and its long-term commercial potential. Analyst Targets Suggest As Much As 950% Upside Potential

Analysts maintain a significantly bullish outlook on (VNRX), citing the disconnect between its current valuation and its commercial trajectory. - Zacks Small-Cap Research maintains a target of $2.95, representing an approximate 950% potential upside from recent levels.
- D. Boral Capital maintains a bullish stance with a $2.55 target, suggesting over 850% upside potential.
- H.C. Wainwright recently updated its bullish rating with a $1.50 target, suggesting over 430% upside potential.
- Freedom Capital Markets holds a $1.00 target, indicating a projected 257% upside potential.
Keep reading to see why we're so excited to be highlighting (VNRX) right now. Inside (VNRX): A New Approach to Early Disease Detection
VolitionRx Limited (VNRX) is a multi-national epigenetics company dedicated to saving lives through the earlier detection of disease. Headquartered in Henderson, Nevada, with significant operations in Belgium, the company has spent over ten years mastering the science of Nucleosomics™. Their patented technology focuses on isolating and analyzing circulating nucleosomes—small segments of chromosomes—that are released into the blood when cells are damaged or diseased. The company's primary platform, Nu.Q®, is designed to be a simple, routine, and affordable blood test that can be integrated into existing clinical workflows. Unlike traditional biopsies that are often invasive and expensive, (VNRX) offers a liquid biopsy solution that provides a window into a patient's health at a molecular level. Their reach extends across human and veterinary medicine, with products like Nu.Q® Vet already available in over 20 countries through major partnerships. In late 2025, (VNRX) reached a pivotal commercial milestone by announcing the first sale of its Nu.Q® Cancer assays for clinical certification in France. This marks the transition of their technology from the laboratory to routine clinical use in a major European hospital network. Furthermore, the company recently solved a major "needle in a haystack" problem in liquid biopsy, achieving a massive 180-fold (18,000%) enrichment of tumor DNA, which could significantly improve the accuracy of early-stage cancer detection.
Two Enormous Target Markets
The market for early disease detection is immense, and (VNRX) is targeting some of the most burdensome conditions in modern medicine. Sepsis alone accounts for approximately one in five deaths globally, and its late detection leads to severe morbidity and high healthcare costs. According to recent business reviews, (VNRX) identifies a $2.8B Total Addressable Market (TAM) for early sepsis detection and management. The inclusion of the Nu.Q® NETs assay in France's "DETECSEPS" program—a real-world evaluation of early sepsis detection—positions Volition to address a critical gap in emergency care. By distinguishing sepsis from non-infectious inflammation, this technology could help clinicians intervene hours earlier, potentially saving countless lives. In oncology, the scope is even larger. (VNRX) estimates the annual TAM for lung cancer screening and management at $2.3B, while the broader multi-cancer early detection and liquid biopsy market represents a staggering $22B annual potential within the next decade. 
By focusing on "low-cost, high-volume" testing, (VNRX) aims to capture significant share in markets traditionally dominated by expensive, complex sequencing. Strategic Commercial Partnerships
(VNRX) has successfully mirrored its veterinary success in the human diagnostic space by securing agreements with healthcare leaders. In the third quarter of 2025, the company signed a research license and exclusive commercial option with Werfen, a global leader in specialized diagnostics, to investigate the clinical utility of Nu.Q® in managing Antiphospholipid Syndrome (APS). Additionally, management is currently in discussions with approximately 10 of the world's leading diagnostic companies, suggesting a steady pipeline of licensing deals that could provide upfront payments and recurring revenue. Operational and Fiscal Position
Recent results highlight a company tightening its belt while scaling its reach. For Q3 2025, (VNRX) reported a 32% year-over-year revenue increase to $0.6M. More importantly, the company reduced its operating expenses by 10% and lowered its net cash usage in operations by 33% compared to the prior year. Following a public offering that secured $6.1M in net proceeds, (VNRX) has bolstered its runway to support the commercial rollout of its human diagnostic assays. The executive team, led by CEO Cameron Reynolds, continues to focus on a capital-efficient model while expanding its intellectual property moat.
7 Key Drivers Putting (VNRX) At The Top Of This Morning's Watchlist —Thursday, January 8, 2026…
1. First Human Commercial Sale: The recent sale of Nu.Q® Cancer assays by (VNRX) to the Hospices Civils de Lyon in France marks the start of routine clinical use and sets a blueprint for European expansion. 2. Analyst Target: One analyst maintains a $2.95 target on (VNRX), representing an approximate 950% upside potential from recent levels. 3. 18,000% DNA Enrichment: The new Nu.Q® Capture-Seq technology developed by (VNRX) achieves 180-fold enrichment of tumor DNA, potentially making it one of the most sensitive tools for early-stage liquid biopsies. 4. National Sepsis Evaluation: Inclusion of (VNRX)'s Nu.Q® NETs assay in France's state-backed "DETECSEPS" program provides a high-profile validation of its potential role as a prognostic tool for organ failure and mortality. 5. Lung Cancer Data Presentation: (VNRX) recently presented two abstracts at the North America Conference on Lung Cancer, highlighting the potential effectiveness of Nu.Q® in detecting and monitoring lung malignancy. 6. Proven Veterinary Success: The Nu.Q® Vet platform from (VNRX) is already being commercialized globally through major distributors, providing a proven "proof of concept" for a high-volume human diagnostic rollout. 7. Tier-1 Partnership Potential: Collaboration between (VNRX) and global diagnostic leaders like Werfen and Hologic supports the potential utility of its technology for large-scale clinical platforms across multiple disease areas. Take A Look At (VNRX) While It's Still Early…

As we look toward the next 12-18 months, the narrative for Volition is shifting from "what if" to "how fast." The company has spent years building a robust moat of intellectual property and clinical evidence, and they are now hitting the execution phase of their business plan. With (VNRX) gaining visibility in the liquid biopsy space, the milestones achieved in late 2025 have laid a strong foundation for a breakout 2026. We will be closely monitoring the upcoming peer-reviewed publications and potential new licensing deals with global diagnostic leaders. The transition of Nu.Q® into routine clinical practice may shape up to be a major potential catalyst that could redefine the company's profile. If you've been tracking where epigenetics is headed, (VNRX) is one little-known company you'll want to keep on your radar. We have all eyes on (VNRX) this morning—Thursday, January 8, 2026. And watch for my next update—it could be hitting any moment.
Alex Ramsay Co-Founder / Managing Editor Krypton Street Newsletter |