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Additional Reading from MarketBeat Media Small-Cap Standouts: These 3 Stocks Rose Over 300% in 2025Written by Leo Miller. Posted: 1/3/2026. 
At a Glance - While small caps as a whole generated lower returns than large caps in 2025, three interesting names bucked this narrative.
- A cancer screening company and two satellite operators saw their shares rise 300% or more.
- See where analysts are forecasting upside and understand vital considerations pertaining to smaller stocks.
In 2025, small-cap stocks underperformed. The Russell 2000 Index, which tracks the performance of 2,000 U.S. small-cap stocks, delivered a total return of about 13% in 2025. That lagged the S&P 500 Index's total return of roughly 18%, which tracks U.S. large-cap stocks. Despite the general underperformance, three names stood out for exceptional gains in 2025. Below, we detail three stocks that returned 300% or more. Our analysis focuses on companies that began 2025 in small-cap territory but have since grown into mid-cap stocks due to their stellar gains. GRAL Catapults on Early Cancer Detection Enthusiasm REVEALED: America just unlocked a $500 trillion asset
Everyone's talking about AI stocks but almost no one is talking about what AI actually runs on.
Nickel. Copper. Cobalt. Manganese.
America just secured exclusive rights to the largest untapped supply on Earth.
One company is already in position and this could be one of the most important AI infrastructure plays heading into 2026. The name and ticker are available here now >>> Healthcare stock GRAIL (NASDAQ: GRAL) rose roughly 380% in 2025, with market capitalization climbing from well under $1 billion to about $3.3 billion. GRAIL's flagship product is the Galleri multi-cancer early detection test. Early detection dramatically improves cancer survival rates, which has driven strong interest in Galleri. Only about five cancers have established, standardized screening methods, yet roughly 70% of cancer deaths come from other types. GRAIL designed Galleri to detect more than 50 types of cancer. In a recent study, the company said Galleri increased early cancer detection by more than sevenfold when added to traditional screening. Today, most Galleri sales are out-of-pocket, but GRAIL expects to apply for premarket approval (PMA) from the U.S. Food and Drug Administration in the first quarter of 2026. If approved, commercial insurers would be much more likely to cover the test, unlocking a substantial sales channel. That potential approval has driven considerable investor enthusiasm. The MarketBeat consensus price target of $97.50 reflects optimism among analysts and implies roughly 14% upside. PL Blasts Off, Combining AI with Geospatial Imagery Planet Labs PBC (NYSE: PL) had a banner 2025, with shares rising nearly 390%. Planet operates hundreds of satellites that collect medium- to high-resolution images of Earth. By combining that imagery with artificial intelligence, the company helps customers make better decisions. Revenue comes from subscriptions to its cloud-based software platform and satellite services. Demand is materializing, particularly from government customers. Its Dec. 10 earnings report drove a one-day 35% jump in the stock after defense and intelligence revenue increased by more than 70%. The company reported a backlog of about $735 million—roughly 2.6 times its trailing 12-month revenue of $282 million—providing a runway for growth. Planet Labs also generated positive free cash flow for the second consecutive quarter. The MarketBeat consensus price target of $14.74 implies about 25% downside. However, the average of targets updated after the company's most recent earnings report is $18.19, which implies roughly 7.7% downside. Planet Labs is worth watching; a significant pullback could present a more attractive entry point. Updated Targets Eye Strong Upside in VSAT After Huge 2025 Run Finally, Viasat (NASDAQ: VSAT) climbed about 305% in 2025, leaving it with a market capitalization near $4.7 billion. Viasat is another satellite company, but it focuses on internet and data connectivity—serving aviation, maritime, and government customers rather than primarily targeting consumer telecom operators like AST SpaceMobile (NASDAQ: ASTS). The company provides in-flight wireless connectivity to thousands of commercial and business aircraft. The U.S. government was Viasat's largest customer in fiscal 2025, accounting for 18% of revenue. (Viasat is currently in fiscal 2026.) Revenues grew just 2% last quarter, but awards rose 17% to nearly $1.5 billion and the backlog climbed to almost $3.9 billion. The MarketBeat consensus price target of $32.75 implies about 5% downside. However, targets updated after Viasat's Nov. 7 earnings report average $49, suggesting roughly 37% upside. GRAL, PL, VSAT: Deep Research Is Paramount GRAL, PL, and VSAT delivered remarkable returns in 2025. Still, investors should remember that smaller, fast-running stocks carry elevated risk and can be highly volatile. Confidence in a company's long-term outlook and thorough due diligence are essential before making investment decisions in names that have experienced such large gains.
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