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This Month's Exclusive Story Small-Cap Standouts: These 3 Stocks Rose Over 300% in 2025Reported by Leo Miller. Posted: 1/3/2026. 
In Brief - While small caps as a whole generated lower returns than large caps in 2025, three interesting names bucked this narrative.
- A cancer screening company and two satellite operators saw their shares rise 300% or more.
- See where analysts are forecasting upside and understand vital considerations pertaining to smaller stocks.
In 2025, small-cap stocks underperformed. The Russell 2000 Index, which tracks the performance of 2,000 U.S. small-cap stocks, delivered a total return of roughly 13% in 2025. That was significantly below the S&P 500 Index's total return of about 18%, which tracks U.S. large-cap stocks. Despite the sector's overall lag, three names stood out for exceptional performance in 2025. Below are three small-cap stocks that returned 300% or more. This analysis focuses on companies that began 2025 in small-cap territory but, thanks to their gains, have since moved into mid-cap range. GRAL Catapults on Early Cancer Detection Enthusiasm While President Trump's official salary is $400,000 per year... his tax returns reveal he's been collecting up to $250,000 PER MONTH from one hidden source. Until recently, most Americans couldn't touch the type of investment that makes up this investment. But thanks to Executive Order 14330, that just changed. If you love investing in disruptive new companies... Discover how to invest in the fund Trump uses to collect this income >> Healthcare stock GRAIL (NASDAQ: GRAL) rose roughly 380% in 2025. Its market capitalization moved from well under $1 billion to about $3.3 billion. GRAIL's primary product is the Galleri multi-cancer early-detection test. Early detection greatly improves cancer survival odds, which has driven significant interest in the product. Only around five types of cancer have standardized screening methods, yet about 70% of cancer deaths come from cancers other than those five. GRAIL designed Galleri to detect more than 50 different cancer types. In a recent study, the company reported that adding Galleri to traditional screening increased early cancer detection by more than seven times. Currently, most Galleri sales come from out-of-pocket payments. GRAIL expects to apply for Premarket Approval (PMA) from the U.S. Food and Drug Administration in the first quarter of 2026. If granted, PMA would substantially increase the likelihood that commercial insurers cover the test, unlocking a potentially large sales channel. That potential approval is a major reason investors remain enthusiastic. The MarketBeat consensus price target of $97.50 reflects analyst optimism, implying roughly 14% upside. PL Blasts Off, Combining AI with Geospatial Imagery Planet Labs PBC (NYSE: PL) enjoyed an exceptional 2025, with shares rising just under 390%. Planet operates a constellation of satellites that capture medium- to high-resolution Earth imagery and combines that data with artificial intelligence to help customers make better decisions. The company generates revenue through subscriptions to its cloud-based platform and satellite services. Demand is materializing, especially among government customers. Its Dec. 10 earnings report sent shares up 35% in one day, with defense and intelligence revenue rising more than 70%. The firm reported a backlog of about $735 million — roughly 2.6 times its last 12 months' revenue of $282 million — which supports the case for significant growth. Planet Labs also posted positive free cash flow for the second consecutive quarter. The MarketBeat consensus price target of $14.74 implies about 25% downside from current levels. However, the average of targets updated after the company's latest earnings report is $18.19, implying roughly 7.7% downside. Planet Labs remains a name to watch; a meaningful pullback could present a more attractive entry point. Updated Targets Eye Strong Upside in VSAT After Huge 2025 Run Last is Viasat (NASDAQ: VSAT), which gained about 305% in 2025 and now has a market cap near $4.7 billion. Viasat is another satellite company focused on internet and data connectivity, more comparable to AST SpaceMobile (NASDAQ: ASTS) in technology but with a different customer mix. Viasat primarily serves aviation, maritime, and government clients rather than consumer mobile carriers. The company provides in-flight wireless connectivity to thousands of commercial and business aircraft. The U.S. government was Viasat's largest customer in fiscal 2025, accounting for 18% of revenue. (Viasat is currently in fiscal 2026.) Revenues grew just 2% year-over-year last quarter, but awards rose 17% to nearly $1.5 billion and the backlog climbed to almost $3.9 billion. The MarketBeat consensus price target of $32.75 implies about 5% downside. However, analyst targets updated after the Nov. 7 earnings report average $49, which suggests roughly 37% upside potential. GRAL, PL, VSAT: Deep Research Is Paramount Overall, GRAL, PL, and VSAT delivered remarkable returns in 2025. While these gains are exciting, investors should remember that smaller companies — especially those that have surged — can be highly volatile. Confidence in a company's long-term prospects is critical to navigating that volatility. Investors should conduct thorough due diligence before making investment decisions in these names.
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