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Exclusive Story Small-Cap Standouts: These 3 Stocks Rose Over 300% in 2025Author: Leo Miller. Published: 1/3/2026. 
In Brief - While small caps as a whole generated lower returns than large caps in 2025, three interesting names bucked this narrative.
- A cancer screening company and two satellite operators saw their shares rise 300% or more.
- See where analysts are forecasting upside and understand vital considerations pertaining to smaller stocks.
In 2025, small-cap stocks underperformed. The Russell 2000, which tracks 2,000 U.S. small-cap companies, delivered a total return of about 13% in 2025 — well below the S&P 500's roughly 18% total return for the year. Despite the sector's overall lag, three small-cap names stood out with exceptional returns. Each gained 300% or more in 2025. We focus on companies that began the year in small-cap territory but, following their gains, have since moved into mid-cap range. GRAL Catapults on Early Cancer Detection Enthusiasm Imagine a bull market so powerful, every single investor became a millionaire. Not by finding the next NVIDIA or Bitcoin, but by owning a simple index fund.
It sounds impossible. Yet it happened – just a short time ago. Now a legendary figure says: "Brace yourselves. It's about to happen here, in America. But fair warning – it could be the worst thing that ever happens to you."
This story has received little coverage in the press. But if history repeats, it could bump tens of millions of Americans into a 7-figure net worth practically overnight. Click here for the full story. Healthcare stock GRAIL (NASDAQ: GRAL) rose about 380% in 2025, lifting its market cap from well under $1 billion to roughly $3.3 billion. Its flagship product is the Galleri Multi-Cancer Early Detection test. Because early detection greatly improves survival odds, Galleri has drawn substantial interest. Only about five cancers have standardized screening methods, yet roughly 70% of cancer deaths stem from other types. Galleri is designed to detect more than 50 cancers. In a recent study, GRAIL reported that adding Galleri to traditional screening increased early cancer detection by more than sevenfold. Currently, Galleri's revenue is mostly from out-of-pocket payments. GRAIL expects to submit a Premarket Approval (PMA) application to the U.S. Food and Drug Administration in the first quarter of 2026. If approved, commercial insurers would be more likely to cover the test, opening a large new sales channel — a prospect that has excited investors. The MarketBeat consensus price target of $97.50 reflects analyst optimism and implies roughly 14% upside. PL Blasts Off, Combining AI with Geospatial Imagery Planet Labs PBC (NYSE: PL) enjoyed a monster 2025, with shares rising nearly 390%. Planet operates hundreds of satellites that capture medium- to high-resolution Earth imagery, which it pairs with artificial intelligence to help customers make more informed decisions. The company sells subscriptions to its cloud-based platform and provides satellite services. Demand is materializing, particularly among government customers. Its Dec. 10 earnings report sent shares up 35% in a day, with defense and intelligence revenue rising more than 70%. The firm reported a backlog of about $735 million — roughly 2.6 times its trailing-12-month revenue of $282 million — which supports potential growth. Planet Labs also posted positive free cash flow for the second consecutive quarter. The MarketBeat consensus price target of $14.74 implies about 25% downside from the time of writing. However, the average of targets updated after the company's latest earnings report is $18.19, which implies roughly 7.7% downside. A significant pullback could make the stock more attractive to long-term investors. Updated Targets Eye Strong Upside in VSAT After Huge 2025 Run Finally, Viasat (NASDAQ: VSAT) gained about 305% in 2025, giving it a market cap near $4.7 billion. Viasat is a satellite communications company focused on internet and data connectivity for aviation, maritime and government customers, differing from peers that primarily target consumer telecom operators. Viasat provides in-flight connectivity to thousands of commercial and business aircraft. The U.S. government was its largest customer in fiscal 2025, accounting for 18% of revenue. (Viasat is currently in fiscal 2026.) Revenues rose just 2% last quarter, but contract awards increased 17% to nearly $1.5 billion and backlog climbed to almost $3.9 billion. The MarketBeat consensus price target of $32.75 implies about 5% downside. However, price targets revised after the company's Nov. 7 earnings report average $49, suggesting roughly 37% upside potential. GRAL, PL, VSAT: Deep Research Is Paramount GRAL, PL and VSAT delivered remarkable 2025 performances. Still, investors should remember that smaller stocks — especially those that have surged — carry higher risk and can be very volatile. Confidence in their long-term prospects and thorough due diligence are essential before committing capital to these names.
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