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Sunday's Exclusive News Small-Cap Standouts: These 3 Stocks Rose Over 300% in 2025Written by Leo Miller. Posted: 1/3/2026. 
In Brief - While small caps as a whole generated lower returns than large caps in 2025, three interesting names bucked this narrative.
- A cancer screening company and two satellite operators saw their shares rise 300% or more.
- See where analysts are forecasting upside and understand vital considerations pertaining to smaller stocks.
In 2025, small-cap stocks generally underperformed. The Russell 2000 Index, which tracks 2,000 U.S. small-cap stocks, delivered a total return of about 13% in 2025. That was noticeably below the S&P 500 Index's total return of roughly 18%, which tracks U.S. large-cap stocks. Despite the broader underperformance, three names stood out for exceptional gains in 2025. Below, we detail three stocks that returned 300% or more. Our analysis focuses on companies that began 2025 classified as small caps but, because of their stellar gains, have since moved into mid-cap territory. GRAL Catapults on Early Cancer Detection Enthusiasm If you want a way to generate consistent market income without chasing volatile AI stocks or complex crypto trades, you'll want to see my new e-book, How To Master The Retirement Trade. It reveals a simple, time-based strategy that targets trades designed to play out in as little as 11 hours — no guesswork, no hype. Claim your free copy of How To Master The Retirement Trade now Healthcare stock GRAIL (NASDAQ: GRAL) rose roughly 380% in 2025. Its market capitalization jumped from well below $1 billion to about $3.3 billion. GRAIL's flagship product is the Galleri multi-cancer early detection test. Early detection greatly improves survival odds, which has generated significant interest in the product. Only about five cancer types have standardized screening methods, yet roughly 70% of cancer deaths come from cancers other than those five. GRAIL designed Galleri to detect more than 50 cancer types. In a recent study, GRAIL reported that Galleri increased early cancer detection by more than sevenfold when added to traditional screening methods. Currently, Galleri's sales are largely out-of-pocket. GRAIL expects to apply for Premarket Approval (PMA) from the U.S. Food and Drug Administration in the first quarter of 2026. If granted, PMA would materially increase the likelihood that commercial insurers cover the test and could open a large new sales channel. That potential approval is a key reason investors are enthusiastic about GRAIL. The MarketBeat consensus price target of $97.50 reflects analyst optimism and implies roughly 14% upside from current levels. PL Blasts Off, Combining AI with Geospatial Imagery Planet Labs PBC (NYSE: PL) enjoyed a massive 2025, with shares rising just under 390%. Planet operates hundreds of satellites that collect medium- to high-resolution Earth imagery. By combining that data with artificial intelligence, the company helps customers make better decisions. Planet generates revenue through subscriptions to its cloud-based software platform and satellite services. Demand is manifesting, particularly among government customers. Its Dec. 10 earnings report sent shares up 35% in one day, with defense and intelligence revenue rising more than 70%. Planet reported a backlog of about $735 million — roughly 2.6 times its last 12 months' revenue of $282 million — which suggests a runway for significant growth. The company also posted positive free cash flow for the second consecutive quarter. The MarketBeat consensus price target of $14.74 implies about 25% downside from the current share price. However, the average of analyst targets updated after the latest earnings report is $18.19, which implies a smaller downside of roughly 7.7%. Planet Labs is worth watching — a significant pullback could create a more attractive entry point. Updated Targets Eye Strong Upside in VSAT After Huge 2025 Run Finally, Viasat (NASDAQ: VSAT) gained approximately 305% in 2025, lifting its market cap to about $4.7 billion. Viasat is another satellite operator but focuses on internet and data connectivity, making it somewhat comparable to AST SpaceMobile (NASDAQ: ASTS). Rather than targeting consumer telecom operators, Viasat primarily serves aviation, maritime and government customers. The company provides in-flight wireless connectivity to thousands of commercial and business aircraft. The U.S. government was Viasat's largest customer in fiscal 2025, accounting for 18% of revenue. (Viasat is currently in fiscal 2026.) Revenues grew only 2% last quarter, but awards rose 17% to nearly $1.5 billion and the backlog climbed to almost $3.9 billion. The MarketBeat consensus price target of $32.75 implies about 5% downside. However, analyst targets updated after the Nov. 7 earnings report average $49, suggesting roughly 37% upside potential. GRAL, PL, VSAT: Deep Research Is Paramount GRAL, PL and VSAT delivered extraordinary returns in 2025. That performance is exciting, but investors should remember that smaller companies — especially those that have posted massive gains — can be highly volatile and carry elevated risk. Confidence in a company's long-term outlook and thorough due diligence are essential before committing capital to these names.
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