Going Green Early, (Nasdaq: CRDL) Could Start Testing Key Technical Chart Levels Wednesday

*Disseminated on Behalf of Cardiol Therapeutics Inc.


Going Green Early, (Nasdaq: CRDL) Could Start Testing Key Technical Chart Levels Wednesday


September 3rd

Greetings Readers,


Cardiol Therapeutics Inc. (Nasdaq: CRDL) steps into green pastures this morning while claiming a top spot on my radar.


And right now I'm looking at CRDL's chart. Here's what I see...


With this early green burst, CRDL has moved above both its 5-Day Simple Moving Average (SMA) and its 5-Day Exponential Moving Average (EMA).


Now, here's where things get interesting.


CRDL's 20-Day SMA and 13-Day EMA are right around $1.15.


If potential resistance breaks down early Wednesday at those levels, support could start developing and continue a recent strong vertical trend which has seen CRDL climb from a sub $.94 level back on August 8th.


Take another look at (Nasdaq: CRDL)'s chart above, read my initial report below, and consider this profile for your watchlist as key chart levels get tested this AM.

-----


Progress in cardiovascular medicine is accelerating, particularly in the search for treatments for inflammatory heart disorders—conditions where few therapeutic options currently exist and patients face significant unmet needs.


Research targeting diseases such as myocarditis and pericarditis is advancing, with encouraging early findings and clinical pipelines moving closer toward meaningful solutions for individuals affected by these challenging conditions.


Driving this momentum is a life sciences company backed by seasoned leadership, united by a clear mission to tackle some of the most urgent issues in cardiac care.


As additional programs take shape, including efforts directed at heart failure, the influence of this team is gaining broader recognition across the hea.lthcare landscape—positioning their work as a notable development for anyone following innovation in heart treatment.


And with topline results recently being released and multiple analyst targets pointing to triple-digit potential upside, this under-the-radar Nasdaq profile has risen quickly to the top of my watchlist.


Consider checking out:


*Cardiol Therapeutics Inc. (Nasdaq: CRDL)*


Cardiol Therapeutics Inc. is a clinical-stage life sciences company focused on developing anti-inflammatory and anti-fibrotic therapies for the treatment of heart disease.


And based on several potential catalysts, (Nasdaq: CRDL) takes over Wednesday's watchlist's top spot. Check them out:


#1. Advancing Therapies That Target Inflammation In The Heart!


#2. Cardiol Therapeutics Enrolling Patients In A Pivotal Phase III MAVERIC Trial.


#3. Cardiol Therapeutics Announced Phase II Topline Results For ARCHER.


#4. Multiple Analyst Targets Point To Triple-Digit Potential Upside!


#5. Near-Term Milestones Could Start Generating Serious Buzz.


But more on those in a second...


Cardiol's Immediate Focus


The company is focused on understanding how inflammation and fibrosis contribute to diseases of the heart and to develop therapies, now in clinical trials for rare cardiac conditions, to target these mechanisms and promote healing.


Pericarditis


Pericarditis is the most common pericardial disease, responsible for about 5% of ER visits for chest pain and 5–26 hospitalizations per 100,000 people each year in the U.S.


Recurrent pericarditis develops in 15–30% of cases, impacting nearly 38,000 patients annually. Each hospitalization can cost $20k–$30k, creating a significant burden.


The only FDA-approved treatment, rilonacept, costs about $20k per month or up to $270k per year. Patients face sharp chest pain, fatigue, and repeat hospital stays, with rare but serious complications like tamponade and constrictive pericarditis. Options remain limited, underscoring the urgent need for new therapies.


Cardiol’s MAVERIC program for recurrent pericarditis has two parts. The first, a Phase II study, is already completed. The second is a pivotal Phase III trial currently enrolling patients across approximately 20 sites in the US, Canada, and Europe. This global, randomized, double-blind, placebo-controlled study is designed to determine whether CardiolRx™ can prevent disease recurrence in high-risk patients and support regulatory approval.

-----


Myocarditis


Acute myocarditis is a leading cause of sudden cardiac death in people under 35 years of age.


Myocarditis is when the heart muscle gets inflamed. It can cause chest pain, trouble with how the heart works, and abnormal heart rhythms. In some cases, it can lead to severe heart failure or even sudden death, especially in people under 35.


Most often, it’s caused by a vi-rus, but it can also come from bacteria, certain medications, mRNA vaccines, or cancer treatments like chemotherapy and immune-

based drugs.


CardiolRx™ was tested in the ARCHER trial, a Phase II study which took place in the US, Canada, Brazil, France, and Israel. The goal was to see if the drug is safe, well tolerated, and helps the heart recover in people with acute myocarditis. The topline results were just announced!

-----


Heart Failure


Heart failure affects more than 64 million people globally and associated heal.thcare costs exceed $30Bn annually in the U.S. alone.


Heart failure is when the heart can’t pump enough blood and oxygen for the body. This can cause shortness of breath, a fast heartbeat, swelling, low energy, and trouble doing everyday activities. Many people with heart failure end up in the hospital often, and it can greatly affect quality of life.


It can be caused by heart attacks, high blood pressure, heart valve problems, heart inflammation (like myocarditis), certain cancer treatments, or inherited conditions.


CRD-38 is Cardiol’s new subcutaneously administered drug formulation targeting heart failure. They’re doing the prep work needed before starting clinical trials to see if it can become a new treatment option.

-----


Product Pipeline

Therapeutic Development - CardiolRx™


CardiolRx™ is an oral treatment in development for serious heart diseases. It works by blocking several inflammation pathways, including the NLRP3 inflammasome, a key driver of the inflammation and scarring seen in pericarditis, myocarditis, and heart failure.


The drug is made to the highest pharmaceutical standards (cGMP) to ensure purity, consistency, and stability. In clinical trials, CardiolRx™ continues to show a profile that is safe and well tolerated, with no serious side effects.


These strong safety results helped Cardiol w-in IND authorization from the FDA approvals to conduct Phase II and Phase III trials in rare heart conditions — recurrent pericarditis and acute myocarditis — giving the company a direct path toward targeting high-value, underserved markets.

The United States Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) for CardiolRx™ for the treatment of pericarditis, which includes recurrent pericarditis. CardiolRx™ is also eligible for FDA ODD in acute myocarditis and European Medicine Agency orphan medicine designations for recurrent pericarditis and acute myocarditis.


Grab Sources And More: CRDL Website. CRDL Presentation.

-----


And as I mentioned earlier, (Nasdaq: CRDL) has several potential catalysts to consider. Take a look:


#1. CRDL Potential Catalyst - Advancing Therapies that Target Inflammation in the Heart!


Cardiol Therapeutics is developing CardiolRx™, an oral canna-bidiol therapy, to treat heart conditions like recurrent pericarditis and acute myocarditis by targeting inflammation.


Promising Phase II results for CardiolRx™ showed improvements in cardiac MRI markers and significant LV mass reduction, with ongoing Phase III MAVERIC trials further evaluating its potential in preventing pericarditis recurrence. 


The company is also advancing CRD-38, a novel subcutaneous drug for heart failure, addressing a critical global health issue.


These therapies demonstrate strong clinical promise and excellent safety profiles.

-----


#2. CRDL Potential Catalyst - Enrolling Patients In A Pivotal Phase III MAVERIC Trial.


Cardiol Therapeutics enrolled the first patient in its pivotal Phase III MAVERIC trial, assessing CardiolRx™ for preventing recurrent pericarditis, earlier this year. 


This randomized, double-blind, placebo-controlled study involves around 110 patients across the US, Canada, and Europe. CardiolRx™, an FDA Orphan Drug-designated oral therapy targeting inflammasome activation, showed in Phase II study significant reductions in pericarditis pain, inflammation, and recurrence rates.


With no widely accessible non-immunosuppressive option currently available, MAVERIC’s outcomes could support a New Drug Application, potentially transforming treatment for patients suffering recurrent pericarditis and addressing a major unmet medical need.

-----


#3. CRDL Potential Catalyst - Cardiol Therapeutics Announced Phase II Topline Results For ARCHER.


Cardiol Therapeutics' Phase II ARCHER trial in acute myocarditis showed that CardiolRx™ notably improved a key heart parameter (LV extracellular volume), trending toward statistical significance and accompanied by significant LV mass reduction.


Multiple cardiac MRI endpoints favored CardiolRx™ over placebo, supporting the drug’s effectiveness.


The therapy demonstrated an excellent safety profile and was well tolerated.


These compelling results provide strong clinical proof of concept, encouraging further development of CardiolRx™ and CRD-38 for heart conditions including myocarditis and heart failure.

-----


#4. CRDL Potential Catalyst - Multiple Analyst Targets Point To Triple-Digit Potential Upside!


Take a look at what we found over at TipRanks:

In case you can't see the fine print, it shares at least 4 Wall Street analysts have provided targets within the last 12 months.


And in each case, their targets are suggesting CRDL to have more than triple-digit upside potential from its chart positioning at close on Tuesday.

-----


#5. CRDL Potential Catalyst - Near-Term Milestones Could Start Generating Serious Buzz.


Cardiol’s near-term roadmap is filled with value-driving, strategic advancements:


  • ARCHER topline results just released (August 6, 2025)
  • Full ARCHER data presentation expected at a major conference (H2 2025)
  • MAVERIC Phase III enrollment ongoing
  • IND enabling work for CRD-38 heart failure program in progress


From a regulatory perspective, the FDA has already granted Orphan Drug Designation for CardiolRx™ in the treatment of pericarditis, and the company also qualifies for additional designations for myocarditis in both the U.S. and the EU.

-----


(Nasdaq: CRDL) Recap - These 5 Potential Catalysts Lead Our Research


#1. Advancing Therapies That Target Inflammation In The Heart!


#2. Cardiol Therapeutics Enrolling Patients In A Pivotal Phase III MAVERIC Trial.


#3. Cardiol Therapeutics Announced Phase II Topline Results For ARCHER.


#4. Multiple Analyst Targets Point To Triple-Digit Potential Upside!


#5. Near-Term Milestones Could Start Generating Serious Buzz.

-----


Coverage is now officially underway on Cardiol Therapeutics Inc. (CRDL).


Be on the lookout for updates coming soon.


Sincerely,

Kai Parker

StockWireNews


(Always Remember The St-ock Prices Could Be Significantly Lower Now From The Dates I Provided.)


*StockWireNews.com (“StockWireNews” or “SWN” ) is owned by SWN Media LLC, a single member limited liability company. Data is provided from third-party sources and SWN is not responsible for its accuracy. Make sure to always do your own research and due diligence on any day and swing profile SWN brings to your attention. Any emojis used do not have a specific defined meaning, and may be used inconsistently. We do not provide personalized in-vest-ment advice, are not in-vest-ment advisors, and any profiles we mention are not suitable for all in-vest-ors.


Pursuant to an agreement between SWN Media LLC and TD Media LLC, SWN Media LLC has been hired for a period beginning on 09/02/2025 and ending on 09/03/2025 to publicly disseminate information about (CRDL:US) (CRDL:CA) via digital communications. Under this agreement, SWN Media LLC has been paid seventeen thousand five hundred USD ("Funds"). To date, including under the previously described agreement, SWN Media LLC has been paid seventy five thousand USD ("Funds"). These Funds were part of the funds that TD Media LLC received from a third party who did not receive the Funds directly or indirectly from the Issuer and does not own st-ock in the Issuer but the reader should assume that the clients of the third party own shares in the Issuer, which they will liquidate at or near the time you receive this communication and has the potential to hurt share prices.


Neither SWN Media LLC, TD Media LLC and their member own shares of (CRDL:US) (CRDL:CA).


Please see important disclosure information here: https://stockwirenews.com/disclosure/crdl-eijdo/#details

Post a Comment

Previous Post Next Post

Contact Form